Tetsuzo Nihei, the legendary Bear Killer, is determined to become the hunter who kills Retar, the last remaining Ezo wolf. Asirpa will never allow this, and she and Immortal Sugimoto race to stop his bloodthirsty quest. Meanwhile, Hijikata, one of the former leaders of the Shinsengumi, assembles a band of death-row escapees to go after the Ainu gold, bringing him face-to-face with Lt. Tsurumi and his 7th Division. In this clash of iron wils, only the strongest can survive.